PULSED FEEDBACK DEFERS CELLULAR DIFFERENTIATION.

Pulsed feedback defers cellular differentiation.

Environmental signals induce diverse cellular differentiation programs.In certain systems, cells defer differentiation for extended time periods after the signal appears, proliferating through multiple rounds of cell division before committing to a new fate.How can cells set a deferral time much longer than the cell cycle? Here we study Bacillus su

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Community-associated methicillin-resistant Staphylococcus aureus clonal complex 80 type IV (CC80-MRSA-IV) isolated from the Middle East: a heterogeneous expanding clonal lineage.

BackgroundThe emergence of community-associated methicillin resistant Staphylococcus aureus (CA-MRSA) has caused a change in MRSA epidemiology worldwide.In the Middle East, the persistent spread of CA-MRSA isolates that were associated with multilocus sequence type (MLST) clonal complex 80 and with staphylococcal cassette chromosome mec (SCCmec) ty

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A glimmer of hope in American pain medicine?

Michael E Schatman US Pain Foundation, Bellevue, WA, USAOver the past 8 years, I have acquired a degree of notoriety relating to my scathing criticism of the badly broken American pain care system.In the three-part series on the crisis in pain care in the United States that I coauthored with Dr Jim Gift Cards Giordano in 2008,1-3 we

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Case Report And Case Series: Is There Room For Them?

This article is part of a special series developed to assist authors in the process of scientific writing and communication.The purpose of the study was to underscore the importance of publishing case reports and case series in the medical and health Gift Cards sciences and to provide insights to guide the authors who wish to submit these types of

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